CLINICAL AND PROGNOSTIC ASSESSMENT OF THE RISK OF DIABETIC RETINOPATHY PROGRESSION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS BASED ON THE CD54 BIOMARKER

V. Yurii; Olena Rybachuk

doi:10.36074/logos-13.03.2026.057

CLINICAL AND PROGNOSTIC ASSESSMENT OF THE RISK OF DIABETIC RETINOPATHY PROGRESSION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS BASED ON THE CD54 BIOMARKER

V. Yurii; Olena Rybachuk

Conference proceedings: Collection of scientific papers «ΛΌГOΣ» with Proceedings of the VII International Scientific and Practical Conference «Theoretical and practical aspects of modern scientific research» (March 13, 2026; Seoul, South Korea)

Section: Medical sciences and Public health

Publication date: 2026/03/13

Pages: 307-310

DOI: 10.36074/logos-13.03.2026.057

ISBN: 978-617-8440-88-6

Publisher: Case Co., Ltd.

Language: en

PDF for indexing Original PDF in OJS archive DOI

Abstract

Type 2 diabetes mellitus remains one of the most prevalent chronic non-communicable diseases worldwide and is characterized by a steady increase in incidence. Of particular clinical significance are its microvascular complications, among which diabetic retinopathy (DR) occupies a leading position as one of the major causes of permanent vision impairment in the working-age population.

Author affiliations

V. Yurii: Education, Institute of Postgraduate Education Bogomolets National Medical University, UKRAINE
Olena Rybachuk: Education, Institute of Postgraduate Education Bogomolets National Medical University, UKRAINE

References

International Diabetes Federation. IDF Diabetes Atlas. 10th ed. Brussels: IDF; 2021.
Yau J.W.Y., Rogers S.L., Kawasaki R. et al. Global prevalence and major risk factors of diabetic retinopathy. Diabetes Care. 2012;35(3):556–564.
Cheung N., Mitchell P., Wong T.Y. Diabetic retinopathy. Lancet. 2010;376(9735):124–136.
Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes. 2005;54(6):1615–1625.
Wilkinson C.P., Ferris F.L., Klein R.E. et al. Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales. Ophthalmology. 2003;110(9):1677–1682.
Tang J., Kern T.S. Inflammation in diabetic retinopathy. Progress in Retinal and Eye Research. 2011;30(5):343–358.
Rybachuk O.V. Influence of factors of the progression of diabetic retinopathy on the content of blood serum cluster of differentiation chemokine CD54 in patients with type 2 diabetes. Medical Science of Ukraine. 2024;20(2):3–10.
Rykov S.O., Rybachuk O.V. Model for assessing the prognostic significance of chemokine CD54 in the progression of diabetic retinopathy in patients with type 2 diabetes. Medical Science of Ukraine. 2025;21(1):55–62.
Rybachuk O.V. Prognostic assessment of the influence of chemokine CD54 on the course of diabetic retinopathy. Archive of Ophthalmology of Ukraine. 2024;12(1):16–21.

[1] International Diabetes Federation. IDF Diabetes Atlas. 10th ed. Brussels: IDF; 2021.

[2] Yau J.W.Y., Rogers S.L., Kawasaki R. et al. Global prevalence and major risk factors of diabetic retinopathy. Diabetes Care. 2012;35(3):556–564.

[3] Cheung N., Mitchell P., Wong T.Y. Diabetic retinopathy. Lancet. 2010;376(9735):124–136.

[4] Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes. 2005;54(6):1615–1625.

[5] Wilkinson C.P., Ferris F.L., Klein R.E. et al. Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales. Ophthalmology. 2003;110(9):1677–1682.

[6] Tang J., Kern T.S. Inflammation in diabetic retinopathy. Progress in Retinal and Eye Research. 2011;30(5):343–358.

[7] Rybachuk O.V. Influence of factors of the progression of diabetic retinopathy on the content of blood serum cluster of differentiation chemokine CD54 in patients with type 2 diabetes. Medical Science of Ukraine. 2024;20(2):3–10.

[8] Rykov S.O., Rybachuk O.V. Model for assessing the prognostic significance of chemokine CD54 in the progression of diabetic retinopathy in patients with type 2 diabetes. Medical Science of Ukraine. 2025;21(1):55–62.

[9] Rybachuk O.V. Prognostic assessment of the influence of chemokine CD54 on the course of diabetic retinopathy. Archive of Ophthalmology of Ukraine. 2024;12(1):16–21.